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Excerpt from Uric Acid: The Chemistry, Physiology, and Pathology of Uric Acid and the Physiological Important Purin Bodies; With a Discussion of the Metabolism in Gout Four years ago the author began a study of the metabolism in certain chronic bone diseases, - rheumatoid arthritis, osteo-arthritis, osteitis deformans, etc., - under the direction of Doctors Goldthwait, Painter and Osgood of Boston. After some preliminary chemical work it seemed advisable to make a very thorough study of the literature concerning the metabolism of the inorganic elements, and also of uric acid, since in the opinion of certain writers uric acid is of great importance in the etiology of the rheumatic diseases. The results of this study led to the conclusion that rheumatic diseases and uric-acid metabolism do not, at the present time, seem to be closely related. The fact that many English writers do not agree with this conclusion, and that there is no complete and reliable account of the metabolism of uric acid to be found in one place, made it seem advisable to publish the results of the work. The view of Haig, the foremost of those who attribute to uric acid a great pathological importance, may be seen from the following extracts. On page 10 he says: "Uric acid affects not only the blood, but influences in a similar way the functions, nutrition, and eventually the structure of every organ and tissue in the body, and as regards infectious diseases has, in some cases, a more important influence than the microbes themselves. As regards the tissues, it controls the production of energy and the production of heat to an extent which, acting as it does from bone to bone throughout the whole of life, cannot but be of enormous importance! But more recent advances have carried us far beyond this, and we can now say with absolute certainty that uric acid controls and conditions the capillary circulation of the whole body, ... and thus regulates the blood pressure, the heart action, the nutrition of the heart and vessels, the nutrition of the tissue, and all the metabolic phenomena which constitute the life of the body to its minutest cells. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

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Author: Francis H McCrudden
Number of Pages: 336 pages
Published Date: 27 Sep 2015
Publisher: Forgotten Books
Publication Country: United States
Language: English
ISBN: 9781330695883
Download Link: Click Here
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